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Milli-Q is a laboratory ultrapure water system developed by Merck Millipore (now part of Merck Group), designed specifically for ultrapure water preparation in biological, chemical, pharmaceutical, and electronics applications. The system effectively removes impurities, ions, organic compounds, and microorganisms from water, ensuring high purity water that meets standards such as ASTM, ISO, and CLSI.

1. Water Quality Grades and Applications

The Milli-Q series water purifiers can produce water of different purity grades to meet various experimental needs:

• Ultrapure Water (Type 1): Suitable for high-demand experiments such as HPLC, ICP-MS, PCR, cell culture, etc.

• Pure Water (Type 2): Suitable for routine chemistry, buffer preparation, and general instrument analysis.

• Deionized Water (Type 3): Suitable for cleaning glassware, reagent preparation, etc.

2. Key Features and Functions

(1) Multi-stage Filtration and Purification Technologies

• Reverse Osmosis (RO): Initially removes 95-99% of ions and organic materials.

• Ion Exchange (EDI/DI): Lowers conductivity and improves water purity.

• Activated Carbon Filtration: Removes volatile organic compounds (VOCs) and chlorine.

• UV Lamp: Effectively reduces TOC (Total Organic Carbon) and inhibits microbial growth.

• Final Filtration (UF/Microfiltration): Ensures particle-free water, suitable for cell culture or ultrapure applications.

(2) Water Quality Monitoring and Data Management

• Built-in Resistivity/Conductivity Sensor: Monitors water quality in real-time (up to 18.2 MΩ·cm).

• TOC Monitoring: Ensures ultra-low organic contamination (available on certain models).

• Touchscreen Display: Shows water quality status and can output historical data for GLP/GMP compliance.

(3) Modular Design and Flexible Installation

• Wall-mounted or Desktop Installation: Saves space.

• Compatible with Water Tanks and Distribution Points: Supplies water to multiple lab locations.

• Foot Pedal or Sensor Water Dispensing: Enhances convenience.

(4) Automatic Cleaning and Maintenance Reminders

• Automatic Flush Function: Prevents internal contamination buildup.

• Filter Replacement Reminders: Ensures stable water quality.

3. Key Models and Applications

• Milli-Q IQ 7000: High-performance ultrapure water system for high-precision analysis and research.

• Milli-Q Direct: Provides both Type 1 and Type 2 water, suitable for general lab needs.

• Elix Series: Uses EDI technology to produce Type 2 water, ideal for instrument analysis and buffer preparation.

• RiOs Series: RO water system for everyday lab use and cleaning applications.

4. Applicable Fields

• Biomedical and Pharmaceutical (Cell culture, PCR, protein purification)

• Environmental Analysis (ICP-MS, AAS, water quality testing)

• Electronics and Semiconductor Industries (Cleaning, etching processes)

• Food and Beverage Testing (HPLC, GC-MS analysis)

Milli-Q water purifiers, with their high purity water, intelligent monitoring, and easy operation, have become the standard equipment for ultrapure water in laboratories worldwide.